2014 Fiscal Year Final Research Report
Elucidation of mechanisms that establish boundaries of dendritic fields in sensory neurons
| Project/Area Number |
25840094
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | The University of Tokyo (2014)
公益財団法人大阪バイオサイエンス研究所 (2013) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 受容野境界 / Wnt5 / Ryk / drl / 神経ー表皮間相互作用 / in vivo イメージング / 感覚神経 / ショウジョウバエ |
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| Outline of Final Research Achievements |
In this study, we investigated molecular and cellular mechanisms by which boundaries of dendritic fields were established in Drosophila sensory neurons. Using a combination of in vivo imaging techniques and molecular genetics, we found that Wnt5 protein prevented dendritic branches from growing across the boundary during the dendrite development.
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| Free Research Field |
生物学
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