Functional analysis of putative output factors of the insect circadian clock.

2014 Fiscal Year Final Research Report

• Project/Area Number: 25840121
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Animal physiology/Animal behavior
• Research Institution: Okayama University
• Principal Investigator: YOSHII Taishi 岡山大学, 自然科学研究科, 准教授 (50611357)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 概日時計 / 体内時計 / キイロショウジョウバエ / 時間生物学

Outline of Final Research Achievements

In Drosophila melanogaster, the molecular mechanism of circadian clock has been well investigated. However, its neuronal mechanism still remains elusive. The Drosophila brain contains about 150 neurons that are responsible for circadian rhythms in behavior. The motivation of this study is to understand how the circadian clock neurons read out time information, which they generate, to downstream neurons. Here, we found that ITP and CCHa1 are new candidate peptides that function as output factors of the clock neurons.

Free Research Field

生物学