2016 Fiscal Year Final Research Report
Toward the development of prognostic indicator and treatment strategy of mitral regurgitation focusing on atrial function
| Project/Area Number |
25850203
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Research Collaborator |
OSUGA Tatsuyuki 北海道大学, 大学院獣医学研究科, 博士研究員
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 左心房 / 心機能 / 心エコー |
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| Outline of Final Research Achievements |
In this study, 1) normal reactivity of left atrium to the volume overload, 2) normal reactivity of left atrium to cardiovascular drugs, 3) changes of left atrial function in cardiac disease, were evaluated. The left atrium has the potential capacity to become double reacting to volume overload and drugs. In the earlier coarse of cardiac disease, the left atrial function increases to adapt the worse condition. However, it decreases gradually with the progression of disease severity, and patients finally die when the worsening of atrial function cross over the certain limit. Left atrium may act as the last defense in animals with cardiac disease.
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| Free Research Field |
獣医学
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