Construction of Anisotropic and Three-Dimensional Molecular-Assembled Systems by Bottom-Up of Synthetic Hetero-Double Helix Molecules and Development of Motional Functions

2014 Fiscal Year Final Research Report

• Project/Area Number: 25860003
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Chemical pharmacy
• Research Institution: Tohoku University
• Principal Investigator: SAITO Nozomi 東北大学, 学際科学フロンティア研究所, 助教 (40636411)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 二重ラセン / ヘリセン / オリゴマー / 液晶 / 自己組織化 / 熱応答 / 異方性

Outline of Final Research Achievements

Described here is the “precise control of molecular properties of ethynylhelicene oligomers based on the molecular design” and “the construction of aniosotropic and three-dimensional molecular-assembled systems utilizing the self-assemblies of homo- and hetero-double helices” in order to integrate the molecular-level transition between double helices and random coils to a muscle-like macroscopic motion. (1) Anisotropic and fluidic thermotropic liquid crystals were obtained by modifying the molecular structure at the termini. Structural transition in the bulk state was shown. (2) Amphiphilic oligomers with hydrophilic termini were synthesized, which showed the thermoresponse inverse to the general one of dimeric aggregates in aqueous media. Formation of vesicular assemblies were also observed. (3) Cyclic bis(ethynylhelicene) oligomers formed lyotropic liquid crystals, which changed into randomly oriented bundles by cooling. The detail of these phenomena was investigated.

Free Research Field

有機化学