2014 Fiscal Year Final Research Report
Target of lysophosphatidylserine on mast cells
| Project/Area Number |
25860041
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biological pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
MAKIDE Kumiko 東北大学, 薬学研究科(研究院), 助教 (30519773)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | リゾリン脂質 / マスト細胞 |
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| Outline of Final Research Achievements |
It is well known that lysophosphatidylserine (LysoPS) has stimulating activity on mast cells. Although several studies suggested the presence of specific target for LysoPS on mast cells, the molecule remains to be identified. In this study, we analysed the responses of TRP channels to LysoPS and found that TPRV1 responds to LysoPS.
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| Free Research Field |
脂質生物学
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