2014 Fiscal Year Final Research Report
The dynamics of spatiotemporal dopamine release
| Project/Area Number |
25860169
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General physiology
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
SHINODA Yo 東京理科大学, 理工学部, 助教 (80403096)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ドーパミン / CAPS2 |
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| Outline of Final Research Achievements |
I established the primary culture method of DAergic neuron from mouse mesencephalon. The subcellular distributions of CAPS2 in the DAergic neuron from VTA and SNc are clarified by using anti-CAPS2 and anti-calbindin antibodies. Primary cultured DAergic neurons from WT and CAPS2 KO mice shows that the release activity of DA is significantly reduced in the DAergic neuron from CAPS2 KO mice.
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| Free Research Field |
神経科学
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