2014 Fiscal Year Final Research Report
Analysis of hemoglobin transport in Plasmodium falciparum
Project/Area Number |
25860309
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Parasitology (including sanitary zoology)
|
Research Institution | Kobe University (2014) Tottori University (2013) |
Principal Investigator |
IRIKO HIDEYUKI 神戸大学, 保健学研究科, 准教授 (60346674)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Keywords | マラリア / ヘモグロビン輸送 / 寄生胞膜 |
Outline of Final Research Achievements |
To elucidate the molecular mechanism and membrane dynamics of hemoglobin transport, I focused in ETRAMP4 (Early Transcribed Protein 4), the membrane proteins expressed in trophozoite stage of Plasmodium falciparum. By immunoelectron microscopy, ETRAMP4 localized in parasitophorous vacuole membrane and uptake by cytostomes, hemoglobin transport vesicles.
|
Free Research Field |
寄生虫学
|