Establishment of the treatment algorithm of the rheumatoid arthritis aimed at clinical, functional and occupational remission.

2015 Fiscal Year Final Research Report

• Project/Area Number: 25860387
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical sociology
• Research Institution: University of Occupational and Environmental Health, Japan
• Principal Investigator: NAWATA Masao 産業医科大学, 医学部, 非常勤医師 (20389430)
• Co-Investigator(Renkei-kenkyūsha): SAITO Kazuyoshi 産業医科大学, 医学部, 准教授 (30279327) ; TANAKA Yoshiya 産業医科大学, 医学部, 教授 (30248562)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 関節リウマチ / メソトレキサート / 寛解 / 臨床的寛解 / 機能的寛解 / 職業的寛解 / TNF阻害薬 / 休薬

Outline of Final Research Achievements

I accumulate continuously a case to correspond to the standard that I showed for a study plan and the method. I analyzed the case using the TNF inhibitor at the same time. At first I performed a stratified analysis for the period of time of the impact between the 10-year use results period, and I analyzed patient backgrounds at the time of the TNF inhibitor baseline.　 In addition, I analyzed it about MTX of the TNF inhibitor combination and examined the most suitable usage of MTX. Furthermore, I paid my attention about bio-free remission of the TNF inhibitor and analyzed it about a factor (patient backgrounds, blood test levels, disease activity, Amount of change of joint preserving effects (Yearly progression) ) at baseline, discontinuation, and after discontinuation.

Free Research Field

リウマチ・膠原病学