2014 Fiscal Year Final Research Report
A study of inhibitory effect of alcohol on the return of spontaneous circulation using a rat model of cardiopulmonary arrest
| Project/Area Number |
25860489
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Legal medicine
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| Research Institution | Kochi University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 心肺蘇生法 / 飲酒者 / 心拍再開 / 救急医学 / 法医学 |
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| Outline of Final Research Achievements |
We investigated whether drinking alcohol has adverse effects on the ability to return of spontaneous circulation (ROSC) by cardiopulmonary resuscitation (CPR) after cardiac arrest. We used a rat model of cardiopulmonary arrest. Three minutes after cessation of natural breathing by hypoxic exposure, CPR with chest compression and oxygen administration were performed to the model rats. There were no significant difference of the rate of ROSC between a group of ethanol administration and a group of saline administration. However, the time between start of hypoxic exposure and cessation of natural breathing in a group of ethanol administration was significantly shorter than that in a group of saline administration. This phenomenon may affect that the rate of ROSC in ethanol groups and a control group are similar.
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| Free Research Field |
法医学
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