The role of adiponectin in appetite and feeding regulation of eating disorder

2015 Fiscal Year Final Research Report

• Project/Area Number: 25860502
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Kagoshima University
• Principal Investigator: Amitani Haruka 鹿児島大学, 医歯学域医学部・歯学部附属病院, 講師 (70535674)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 摂食障害

Outline of Final Research Achievements

Anorexia nervosa (AN) continues to be a refractory disease because of its unknown pathogenesis. The role of adiponectin in AN has not been clarified. Moreover, few reports have described the relations between adiponectin isoforms and AN in the physical and psychological states. Therefore, we measured plasma adiponectin and its isoforms levels in patients with AN to examine their roles in AN. Total and high molecular weight adiponectin levels were significantly decreased only in obesity although they tended to decrease in AN-R. There was no relationship between klotho and total adiponectin levels or klotho and respective adiponectin isoform levels in the entire study population.

Free Research Field

心身医学