2014 Fiscal Year Final Research Report
study of the pathogenesis of functional dyspepsia using breath test and ultrasonic method
Project/Area Number |
25860505
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
General internal medicine(including psychosomatic medicine)
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Research Institution | Yokohama City University |
Principal Investigator |
SEKINO Yusuke 横浜市立大学, 附属病院, 助教 (40622577)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Keywords | 機能性胃腸症 / 呼気法 / 超音波法 |
Outline of Final Research Achievements |
We revealed that oral sumatriptan administration enhanced gastric accommodation after the ingestion of liquid nutrients, but had no significant effect on antral contractions or intragastric distribution in healthy subjects. Single-dose sitagliptin intake had no significant influence on the rate of liquid gastric emptying in asymptomatic volunteers. 100µg ramosetron pre-treatment enhances the early gastric emptying of liquid nutrients, but 5 µg ramosetron pre-treatment enhances the early gastric emptying of liquid nutrients. The gastric transit time(GTT) measured by (video capsule endoscopy)VCE cannot serve as asubstitute for the gastric emptying time measured by the 13C breath test.
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Free Research Field |
消化管運動
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