2015 Fiscal Year Final Research Report
A study of role of phospholipase A2 and phospholipase A2 receptor in cardiovascular regeneration and development of new drug for cardiovascuar disease
| Project/Area Number |
25860591
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Tokyo Metropolitan Institute of Medical Science (2014-2015)
University of Yamanashi (2013) |
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Principal Investigator |
WATANABE Kazuhiro 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員 (50535549)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | ホスホリパーゼA2受容体 / 心血管病 |
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| Outline of Final Research Achievements |
This study was aimed to examine a possible role of secretory PLA2 and PLA2 receptor in cardiovascular regeneration, and to develop a new drug for prevention from cardiovascular diseases. As a result, PLA2R inhibit cardiac rupture after myocardial infarction by increasing migrations of fibroblasts to the infarcted lesion.
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| Free Research Field |
循環器疾患と脂質代謝
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