2014 Fiscal Year Final Research Report
Development of new biomarker of interstitial pneumonia and drug-induced lung disease
| Project/Area Number |
25860663
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Kurume University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HOSHINO Tomoaki 久留米大学, 内科学講座呼吸器・神経・膠原病内科部門, 主任教授 (00261066)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ぺリオスチン / 間質性肺炎 / バイオマーカー |
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| Outline of Final Research Achievements |
Proposal: Development of new biomarker of interstitial lung disease and drug-induced lung disease.
Result: We showed that periostin as extracellular matrix protein was new serum biomarker of interstitial lung disease.Specifically, we showed that serum periostin level had high sensitivity and specificity as a diagnostic biomarker using ROC analysis. Moreover, we showed that periostin was predictor of decline of pulmonary function and survival by statistical analysis.
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| Free Research Field |
呼吸器内科
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