Five years post-delivery kidney function evaluation of preeclampsia, gestational hypertension and gestational proteinuria women.

2015 Fiscal Year Final Research Report

• Project/Area Number: 25860696
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Kidney internal medicine
• Research Institution: National Center for Child Health and Development
• Principal Investigator: Mito Asako 国立研究開発法人国立成育医療研究センター, 周産期・母性診療センター母性内科, 医員 (20468474)
• Research Collaborator: Arata Naoko 国立成育医療研究センター, 周産期・母性診療センター母性内科, 医長 ; Horikawa Reiko 国立成育医療研究センター, 生体防御系内科部内分泌・代謝科, 医長 ; Sakamoto Naoko 東邦大学, 看護学部社会疫学研究室, 准教授
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 妊娠高血圧症候群 / 慢性腎臓病予後 / 出産後腎機能 / 妊娠高血圧腎症 / 妊娠高血圧 / 妊娠蛋白尿

Outline of Final Research Achievements

Hypertensive disease in pregnancy (HDP) is known as a strong risk factor for future end-stage renal disease. However, subsequent and early kidney function post-delivery has not been thoroughly researched in Japan. In this study, we examined renal function of women five years post preeclampsia, gestational hypertension and gestational proteinuria pregnancies. We found estimated glomerular filtration rate (eGFR) is lower than that of normotensive pregnancy five years after delivery. However additional cases are needed to evaluate comprehensive results.

Free Research Field

高血圧・腎臓内科学