2015 Fiscal Year Final Research Report
Research on mechanisms regulating incretin secretion by nutrients
| Project/Area Number |
25860748
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Metabolomics
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| Research Institution | Kobe University |
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Principal Investigator |
Daisuke Yabe 神戸大学, 医学(系)研究科(研究院), 准教授 (60378643)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | インクレチン / 栄養素 / 食べる順番 |
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| Outline of Final Research Achievements |
Mechanisms regulating incretin secretion in response to various nutrients were investigated in humans and cultured cells. Cultured cell models were established to study signaling and metabolism underlying regulation of incretin secretion. Varying incretin response to nutrients were evaluated in humans. Notably, order of nutrients exposed affect incretin secretion. This study now gains strong attention as medical nutritional therapy for management of type 2 diabetes.
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| Free Research Field |
糖尿病学、病態栄養学、内分泌学
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