Engraftment of Human Hematopoietic Stem Cells in Sheep after in Utero Transplantation

2014 Fiscal Year Final Research Report

• Project/Area Number: 25860793
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Hematology
• Research Institution: Jichi Medical University
• Principal Investigator: ABE Tomoyuki 自治医科大学, 医学部, 助教 (20610364)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 再生医学 / 幹細胞 / トランスレーショナルリサーチ / 移植・再生医療 / 応用動物

Outline of Final Research Achievements

The generation of definitive (engraftable) human hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) has been a major challenge in hematology. We are trying to generate hematopoietic chimera in sheep with human iPSCs.

Free Research Field

医歯薬学