Clinical application of heart rate variability for child-onset neuromuscular diseases

2016 Fiscal Year Final Research Report

• Project/Area Number: 25860877
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pediatrics
• Research Institution: Nagoya City University
• Principal Investigator: HATTORI Ayako 名古屋市立大学, 大学院医学研究科, 助教 (80444975)
• Research Collaborator: HAYANO Junichiro ; MIZUNO Kumiko ; KURU Satoshi ; MOTOHASHI Yuko
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 予後予測 / 心拍変動 / 神経筋疾患

Outline of Final Research Achievements

The goal of this study is to find prognostic factors of neuromuscular disease, using heart rate variability. Here we investigated the relation between heart rate variability and mortality of Duchenne muscular dystrophy. We analyzed 77 24-hour holter ECG data of15 patients who died. Each parameters of heart rate variability was depressed nearing to death, statistically significant. But there were no significant correlations between arrhythmia and mortality. These results was similar to previous reports of myocardial infarction. Heart rate variability was suggested to predict the prognosis of patients with neuromuscular diseases.

Free Research Field

小児科