2015 Fiscal Year Final Research Report
A longitudinal study of relationship between depressive symptoms and cognitive function in individuals with at-risk mental state for psychosis
| Project/Area Number |
25860984
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 精神病発症リスク状態 / ARMS / 認知機能 / 神経心理学 / うつ / 機能 / 社会機能 / 縦断研究 |
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| Outline of Final Research Achievements |
The relationship between the longitudinal changes of depressive symptoms and cognitive function in individuals with at-risk mental state (ARMS) was investigated. Thirty-six ARMS participants were followed up and assessed with their depressive symptoms and cognitive performance at baseline, six month, and twelve month after intake. The changes in depressive symptoms in six and twelve month follow-up from baseline were significantly correlated with those of cognitive function. Furthermore, a multiple regression analysis revealed that not the change of cognitive function but that of depressive symptoms would contribute to the improvement of functioning in ARMS subjects.
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| Free Research Field |
医歯薬学
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