2014 Fiscal Year Final Research Report
Development of an applicator for treating shallow and moving tumors with respiratory-gated spot-scanning proton therapy using real-time image guidance
| Project/Area Number |
25861049
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 陽子線治療 / スポットスキャニング照射 / 呼吸性移動 |
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| Outline of Final Research Achievements |
An applicator was developed for treating shallow and moving tumors (e.g., lung tumors) with respiratory-gated spot-scanning proton therapy using real-time image guidance. The mechanical design was considered such that the Bragg peaks are placed at the patient surface while a sufficient field of view (FOV) of fluoroscopic X-rays was maintained during the proton beam delivery. To reduce the treatment time maintaining the robustness of the dose distribution with respect to motion, a mini-ridge filter (MRF) was sandwiched between two energy absorbers. The measurements were performed to obtain data for beam modeling and to verify that a pencil beam dose distribution does not vary with its lateral position. The treatment planning study of lung patients showed that indeed the spot-scanning proton beam can be delivered to shallow and moving tumors in a sufficiently short time and with high accuracy by installing the developed applicator at the treatment nozzle.
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| Free Research Field |
陽子線治療物理
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