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2014 Fiscal Year Annual Research Report

直腸癌術前VMAT治療中の線量分布変化

Research Project

Project/Area Number 25861075
Research InstitutionThe University of Tokyo

Principal Investigator

山下 英臣  東京大学, 医学部附属病院, 講師 (70447407)

Project Period (FY) 2013-04-01 – 2015-03-31
Keywords直腸の動き / 直腸癌 / コーンビームCT / 強度変調放射線治療 / 標的体積内同時ブースト
Outline of Annual Research Achievements

PURPOSE:
The purpose of the present study was to quantify the inter-fractional motion of the rectum and the rectal and bladder volumes using CBCT scans taken during chemoradiation therapy (CRT) for rectal cancer. Also, assessment was made for a better margin for simultaneous integrated boost - intensity modulated radiation therapy (SIB-IMRT) for rectal cancer.

32症例の直腸癌術前症例で、VMAT-IMRT直前の位置合わせのCBCTを用いて直腸と膀胱の容積ならびに直腸の位置を調べた。CBCTは各症例の治療日1・7・13・19・25日目のものを使用。標的体積を直腸が超えていた割合は、20.7%であった。3mmのマージンに入らなかった割合は7.2%、5mmで3.9%、7mmで2.1%、10mmで0.7%、15mmで0.1%はみ出ていた。膀胱容積とはみ出る割合には相関関係は見られなかった。

本内容は『Radiation Oncology (2015) 10:2』に発表済み。

  • Research Products

    (1 results)

All 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Analysis of motion of the rectum during preoperative intensity modulated radiation therapy for rectal cancer using cone-beam computed tomography2015

    • Author(s)
      Hideomi Yamashita*, Ryousuke Takenaka, Akira Sakumi, Akihiro Haga, Kuni Otomo and Keiichi Nakagawa
    • Journal Title

      Radiation Oncology

      Volume: 10 Pages: 2

    • DOI

      10.1186/s13014-014-0311-6

    • Peer Reviewed / Open Access

URL: 

Published: 2016-06-01  

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