Study on optimization of the segmental acquisition method to improve the visualization of the cancer lesion in the nuclear medicine diagnosis.

2016 Fiscal Year Final Research Report

• Project/Area Number: 25861115
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Tsukuba International University (2014-2016); Ibaraki Prefectural University of Health Science (2013)
• Principal Investigator: tsuda keisuke つくば国際大学, 医療保健学部, 講師(移行) (00598146)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 核医学検査 / 分割収集法 / FDG-PET検査 / 呼吸運動

Outline of Final Research Achievements

In this study, we aimed at the optimization of the segmental acquisition method to improve the visualization of the cancer lesion in the nuclear medicine diagnosis. We evaluated the usefulness of the segmental acquisition method in clinical FDG-PET tests for rectal cancer. As for the segmental acquisition method, detection of cancer lesions and image quality were significantly superior to the conventional continuous acquisition method, and clinical usefulness was suggested. Then, we evaluated the effects of respiratory motion on the quantitatively of pulmonary nodules on FDG-PET test by experiments using a dynamic thorax phantom. Based on the results of these experiments, we derived a new correction method for the quantitatively of pulmonary nodules on FDG-PET test. Our newly proposed methods could correct the decrease of counts of pulmonary nodules due to partial volume effects and motion effects with acceptable errors.

Free Research Field

医歯薬学