Development of advanced data acquisition methods for quantitative SPECT

2015 Fiscal Year Final Research Report

• Project/Area Number: 25861131
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyoto College of Medical Science
• Principal Investigator: MATSUMOTO Keiichi 京都医療科学大学, 公私立大学の部局等, 講師 (60393344)
• Research Collaborator: FUJITA Masaki ; MURAKAMI Mikoto ; WADA Ryota
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: SPECT / 非対称法 / 補間投影データ法 / 逐次近似画像再構成 / 緩和係数

Outline of Final Research Achievements

The purpose of this study was to develop a Hybrid SPECT reconstruction method by a combination of the asymmetric SPECT acquisition, IPDE (Interpolated Projection Data Estimation) method and modified DRAMA (Dynamic RAMLA) reconstruction algorithm. A Hybrid SPECT reconstruction method was evaluated to a two-dimensional Shepp-Logan head numerical phantom with statistical noise and a 3-D brain phantom. Quality of the reconstructed images was evaluated in terms of mean structural similarity (MSSIM) values. The Hybrid SPECT reconstruction method showed faster resolution recovery with lower noise than the asymmetric SPECT acquisition and IPDE method and yielded acceptable images in 2 or 3 iteration. The sensitivity of a gamma camera was also maintained virtually constant during the 3 years.

Free Research Field

医歯薬学・医用画像情報解析学