2015 Fiscal Year Final Research Report
Development of the new therapy using the ray radiation on inflammatory bowel disease
| Project/Area Number |
25861205
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
|
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| Research Institution | Oita University |
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Principal Investigator |
|
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | LED光線 / 光線療法 / DSS誘導大腸炎 / disease activity index |
|---|
| Outline of Final Research Achievements |
The body surface radiation to the 2.5% dextran sulfate sodium - induced colitis mouse of LED rays significantly reduced disease activity index score of the colitis and significantly decreased shortening of the length of large intestine.
Whereas the significant change of the lymphocytes marker (CD4, CD8, B220, Foxp3) in murine spleen irradiated with LED rays was not found. The LED rays wavelength (patent pending) of a certain wavelength has a colitis improvement effect.
A search of the further mechanism, optimal condition may lead to new therapy for inflammatory bowel disease.
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| Free Research Field |
医歯薬学
|
