Cerebral network plasticity revealed by intraoperative cortico-cortical evoked potentials

2015 Fiscal Year Final Research Report

• Project/Area Number: 25861273
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Neurosurgery
• Research Institution: Kyoto University
• Principal Investigator: Kikuchi Takayuki 京都大学, 医学(系)研究科(研究院), 助教 (40625084)
• Co-Investigator(Renkei-kenkyūsha): KUNIEDA Takeharu 京都大学, 大学院医学研究科, 講師 (60609931) ; MATSUMOTO Riki 京都大学, 大学院医学研究科, 准教授 (00378754)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: cortical function / cerebral network / evoked potential / functional plasticity

Outline of Final Research Achievements

Cortico-cortical evoked potential (CCEP) was reliably recorded during neurosurgical procedure and can trace the function of language connection through dorsal language pathway. We also applied the same method for ventral language pathway and obtained CCEP on temporal cortex. The pre-and postoperative neurophychological testing revealed removal of the lesion adjacent to this pathway had an influence to the semantic processing with a laterality. We also revealed that the function improved in the postoperative course, indicating functional plasticity.

Free Research Field

cerebral funcitonal network