2014 Fiscal Year Final Research Report
The effect of anesthetics on proopiomelanocortin gene expression
| Project/Area Number |
25861373
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology
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| Research Institution | Kyoto University |
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Principal Investigator |
MIZOTA Toshiyuki 京都大学, 医学(系)研究科(研究院), 助教 (80596198)
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| Co-Investigator(Renkei-kenkyūsha) |
FUKUDA Kazuhiko (90199224)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | プロオピオメラノコルチン / 下垂体 / 麻酔薬 |
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| Outline of Final Research Achievements |
We examined the effect of intravenous anesthetics on proopiomelanocortin gene expression in pituitary cell lines.
Ketamine or dexmedetomidine did not affect the proopiomelanocortin gene expression. Propofol dose-dependently enhanced the proopiomelanocortin gene expression.
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| Free Research Field |
麻酔科学
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