2014 Fiscal Year Final Research Report
Elucidation of the cancer recurrence restraint mechanism of the epidural anesthesia
| Project/Area Number |
25861400
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Anesthesiology
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
IGARASHI Toru
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | 硬膜外麻酔 / がん抑制 / Th1/Th2バランス / Th17 / 炎症性サイトカイン / NK活性 |
|---|
| Outline of Final Research Achievements |
We performed a study to search the change of a cancer recurrence and the perioperative function of immunity, based on the hypothesis ‘Epidural anesthesia maintains the function of natural killer cells and T cells, consequently suppress the cancer multiplication', using the rat long-term epidural anesthesia model which has been already established in our laboratory. We are not able to observe the influence that an epidural anesthesia gave Natural killer cell and T cell in this study. Further studies are warranted to clarify relationship between epidural anesthesia and cancer recurrence.
|
| Free Research Field |
麻酔学
|
