2014 Fiscal Year Final Research Report
Evaluation of a novel amino peptidase Laeverin especially expressed on human extravillous trophoblast.
| Project/Area Number |
25861490
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kyoto University |
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Principal Investigator |
HORIE AKIHITO 京都大学, 医学(系)研究科(研究院), 助教 (30535836)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | EVT / 免疫回避 / 血清マーカー |
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| Outline of Final Research Achievements |
We made the study of laeverin which was released from EVT and combined with immune cells. As recombinant laeverin altered the morphology of villous cells, we suspected laeverin was associated with the immunological escape mechanism.
And we also evaluated the possibility of laeverin could be a prospective marker for the PIH. As we detected the declining trend for the laeverin serum level of PIH patients, we suspected laeverin would be the predictive marker.
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| Free Research Field |
生殖内分泌
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