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2015 Fiscal Year Final Research Report

C/EBP alpha is promotes the pathogenesis of endometriosis.

Research Project

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Project/Area Number 25861500
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionOita University

Principal Investigator

KAWANO YUKIE  大分大学, 医学部, 講師 (60516128)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywords子宮内膜症 / エピジェネティクス
Outline of Final Research Achievements

Accumulating evidence suggests that various epigenetic aberrations play definite roles in the pathogenesis of endometriosis. Our findings suggest that an epigenetically suppressed tumor suppressor gene is involved in the pathogenesis of endometriosis by creating the proliferative, antiapoptotic,and
other disease-specific characteristics of endometriosis. The results also suggest that histone deacetylase inhibitors are promising agents for the treatment of endometriosis.

Free Research Field

産婦人科学

URL: 

Published: 2017-05-10  

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