2014 Fiscal Year Final Research Report
Immunological features in the patients with recurrent eosinophilic chronic rhinosinusitis
| Project/Area Number |
25861586
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | 好酸球性副鼻腔炎 / 内視鏡下鼻内手術 / 一酸化窒素 |
|---|
| Outline of Final Research Achievements |
Eosinophilic chronic rhinosinusitis has a tendency of recurrence after the surgery. We classified the patients who had the surgery as good prognosis group, steroid effectiveness group, and steroid resistance group. In steroid resistance group, mucosal eosinophil count and IL-5 mRNA tended to higher, but significantly difference. In addition, the measurement of nasal FeNO may be an effective tool that assess the sinus mucosa condition during postoperative period.
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| Free Research Field |
鼻科学
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