Distinction of the factor with which a medicine search for improvement of results and a filtration vesica are concerned insufficiently after a glaucoma operation

2014 Fiscal Year Final Research Report

• Project/Area Number: 25861613
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Ophthalmology
• Research Institution: Tohoku University
• Principal Investigator: WATANABE Ryo 東北大学, 医学(系)研究科(研究院), 非常勤講師 (70625293)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 緑内障 / 線維柱帯切除術 / MIP1-β / サイトカイン

Outline of Final Research Achievements

Medicine mitomycin C which is used for the time of fiber pillar area resection which passes to glaucoma has epithelia anterius corneae toxicity. When I did medicine search of a TENON vesica fiber sprout cell growth using the existence medicine library restrained in peculiar way, a hit compound was found 10 pills.
The previous aqueous humor was extracted at the time of a glaucoma operation, and correlation with the filtering method function of 6 months and the filtering method structure was considered after an operation with 27 kinds of site Cain density using Bio - Plex. MIP1-β admitted significant correlation in the ocular pressure and the filtration vesica structure after an operation.

Free Research Field

緑内障