2014 Fiscal Year Final Research Report
Effect of intraoperative trehalose in trabeculectomy using rabbit eyes
| Project/Area Number |
25861615
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Research Collaborator |
HOSHI Sujin
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | トレハロース / 癒着防止 / 緑内障 / 眼科 |
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| Outline of Final Research Achievements |
This study was conducted to examine the effect of trehalose for anti-fibrosis in rabbit eyes undergoing trabeculectomy. No significant inflammation and infection were observed in both trehalose and control group with slit-lamp examination. With anterior segment polarization-sensitive optical coherence tomography, increase of phase retardation was shown around the bleb in trehalose group. The present result indicates that intraoperative use of trehalose may inhibit the formation of postoperative adhesion around the conjunctiva and sclera.
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| Free Research Field |
緑内障手術、硝子体手術
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