2014 Fiscal Year Final Research Report
Development of cultured composite skin with a vessel forming ability
| Project/Area Number |
25861708
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
|
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| Research Institution | Tokai University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | 表皮角化細胞 / 真皮線維芽細胞 / 培養皮膚 / 血管内皮前駆細胞 |
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| Outline of Final Research Achievements |
Keratinocytes and fibroblasts were respectively co-cultured with endothelial progenitor cells obtained by a serum-free quality and quantity control culture (QQc). We compared the number of cells of keratinocytes and fibroblasts in co-cultured with the number of their in mono-cultured after 48hours. As a result, for keratinocytes, the increase in cell number of approximately 29% (n = 1) was found in co-culture. For fibroblasts, the increase in cell number of approximately 11% (n = 3) was found in co-culture. It is reasonable to suppose that QQc cells have a proliferative effect on each cells.
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| Free Research Field |
形成外科学
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