Elucidation of factors which affects bone healing in teeth extraction sockets.

2016 Fiscal Year Final Research Report

• Project/Area Number: 25861837
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Niigata University
• Principal Investigator: MIKAMI Emi 新潟大学, 医歯学総合病院, 医員 (20419328)
• Project Period (FY): 2014-02-01 – 2017-03-31
• Keywords: 抜歯窩治癒 / 歯槽骨生検 / マイクロCT / 骨リモデリング / 骨形態計測 / 微細骨梁構造 / ヒト

Outline of Final Research Achievements

The purpose was to determine whether the bone remodeling in human tooth extraction sockets attained points of relative stability, and if so, at which post-extraction times such points would be reached. Subjects were 5 males and 31 females receiving implant operations or dental transplantation surgery. Post-extraction times ranged from 1.6 to 360 months. The alveolar bone biopsy samples were analyzed using micro-computed tomography and three-dimensional bone morphometry. Various alveolar bone parameters were plotted against post-extraction times, and a stepwise piecewise linear regression analysis was performed. The period between 7 and 12 months post-extraction was found to contain the greatest number of inflection points. Once these changes reached their respective inflection points, the time-related changes stopped. In the human alveolar bone, dynamic remodeling of the trabecular structure was found to continue to occur until the 7th - 12th month post-extraction.

Free Research Field

補綴系歯学