2014 Fiscal Year Final Research Report
Development and research of super-membrane
Project/Area Number |
25861861
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Prosthodontics/ Dental materials science and
|
Research Institution | Iwate Medical University |
Principal Investigator |
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Keywords | 生体材料 / スーパーメンブレン / アパタイト / コラーゲン複合体 / ハイドロゲル / 硬組織再生 |
Outline of Final Research Achievements |
Membranes prepared by pressing of nano-apatite/collagen composites can be called super-membrane because they exhibited excellent osteo-conduction in rat calvarial defects. These membranes were gradually bio-absorbed while osteoclasts played a major role. Osteoclasts adhered and metabolized on aggregates of nano-apatite in collagen matrix. Near the membranes, osteoblasts actively formed new bones, leading to bone remodeling. As s result, it was considered that osteo-conduction was established. Uses of growth factors and chemicals were not needed, and it was thought that prepared super-membranes could be clinically employed in near futures.
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Free Research Field |
補綴・理工系歯科学
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