2014 Fiscal Year Final Research Report
Differentiation potency analysis of maxillofacial genetic disease derived iPS cells by serum-free embryoid culture
| Project/Area Number |
25861945
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
NABESHIMA Kou 広島大学, 大学病院, 歯科診療医 (10550999)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | iPS細胞 / 再生医療 |
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| Outline of Final Research Achievements |
Healthy subject and cleidocranial dysplasia derived iPS cells was generated the cell mass called the embryoid body using activin A. This embryoid body was cultured for a long term of 30 days and analyzed it about the induced organization.Tissue section prepared cultured embryoid body, which has examined histologically, not showed clear cartilaginous tissue. However, tissue section staining and genetic analysis suggested that induced embryoid body have been cartilaginous tissue of maxillofacial region.
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| Free Research Field |
口腔外科
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