2015 Fiscal Year Final Research Report
Investigation of the association between periodontal disease and arteriosclerosis in a rural Japanese population: The Ohasama Study
Project/Area Number |
25862072
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Social dentistry
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Research Institution | Tohoku University |
Principal Investigator |
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 前向きコホート / 動脈硬化 / 歯周病 |
Outline of Final Research Achievements |
The purpose of this study was to clarify the association between periodontal disease and arteriosclerosis in a general rural Japanese population, taking into account the different pathological conditions indicated by the respective indices evaluated. The study cohort comprised 409 individuals at least 55 years of age residing in Ohasama, rural community in northern Japan. The probing pocket depth was significantly related to brachial-ankle pulse wave velocity (baPWV). On the other hand, the bone loss was significantly associated with augmentation index (AI). In a general rural Japanese population, periodontal disease was associated with arterial stiffness, and this association was found to have different characteristics depending on the properties of the indices evaluated. This result suggests that maintaining good oral hygiene through periodontal treatment is effective for preventing and mitigating different arteriosclerosis-related pathological conditions.
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Free Research Field |
医歯薬学
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