Synthesis and morphological control of antibacterial elements substituted Hydroxyapatite

2014 Fiscal Year Final Research Report

• Project/Area Number: 25870061
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering; Structural/Functional materials
• Research Institution: Tohoku University
• Principal Investigator: SATO MITSUTAKA 東北大学, 金属材料研究所, 助教 (10547706)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 抗菌性 / ハイドロキシアパタイト / 水溶液プロセス / X線吸収微細構造

Outline of Final Research Achievements

In order to develop novel artificial alternates of our hard tissue which prevent some infections during and after orthopedic surgery, antibacterial element substituted HAp powders were prepared based on the aqueous solution process, and the effect of antibacterial element substitution on the crystal phase, microstructure, antibacterial property and other properties were investigated.
Although it is possible to provide a high antibacterial property to HAp by Ag addition, the solid solution limit of Ag was a very small, and most of the added Ag existed as an Ag metal. In the case of Cu addition, it was possible to substitute about 10 mol% for Ca of HAp, and Cu-substituted HAp sample showed similar antibacterial property to that of Ag-substituted HAp.

Free Research Field

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