2014 Fiscal Year Final Research Report
Difference of adipocyte function between superficial and deep subcutaneous fat tissue
| Project/Area Number |
25870138
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
Metabolomics
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| Research Institution | Chiba University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | 脂肪移植 / 皮下脂肪 / エピジェネティクス |
|---|
| Outline of Final Research Achievements |
Subcutaneous fat tissue is frequently used as a donor site of fat or adipocyte grafting. Subcutaneous fat tissue is anatomically separated into two layers by superficial fascia. Superficial fat tissue and deep fat tissue have different function basing on different anatomical structure. The difference in adipocyte function, however, between two layers is still unclear. Our result showed that cell survivability of adipocyte of superficial layer is superior to that of deep layer. Adipocyte differentiation potential is superior in superficial adipocyte compared to deep adipocyte. The difference in epigenetic modification can be one of the causes creating different cell function between two layers.
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| Free Research Field |
脂肪移植学
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