Development of objective evaluation for wound pain in eldery patients with chronic wounds

2015 Fiscal Year Final Research Report

• Project/Area Number: 25870179
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gerontological nursing; Clinical nursing
• Research Institution: The University of Tokyo
• Principal Investigator: TAMAI Nao 東京大学, 医学(系)研究科(研究院), 助教 (80636788)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 疼痛 / 慢性創傷 / 高齢者 / 滲出液

Outline of Final Research Achievements

To clarify the associations between the self-evaluated pain status and, skin temprature and two pain biomarker candidate in exudate from venous leg ulcer (VLU) for establishment of an objective pain evaluation. Each participant with VLU self-evaluated their pain status at each examination using the numerical rating scale and the short-form McGill Pain Questionnaire 2. The NGF and S100A8/A9 concentrations in the VLU exudate were measured by enzyme-linked immunosorbent assay. The association between each pain status and, skin temprature and the two standardized protein concentrations was evaluated. Thirteen participants were analyzed. The pain intensity of the high temperature group was significantly higher than the normal temperature group. The standardized NGF concentration was negatively correlated with continuous, intermittent, and neuropathic pain. The standardized S100A8/A9 concentration was positively correlated with present pain intensity.

Free Research Field

老年看護学、創傷看護学