Pain control for chronic pain patients - for tailor-made medicine-

2015 Fiscal Year Final Research Report

• Project/Area Number: 25870204
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Surgical dentistry; Anesthesiology
• Research Institution: Meikai University (2015); Tokyo Medical and Dental University (2013-2014)
• Principal Investigator: Oono Yuka 明海大学, 歯学部, 准教授 (70451961)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: CPM / DNIC / 慢性疼痛患者 / 定量的疼痛評価 / 疼痛コントロール

Outline of Final Research Achievements

Conditioned pain modulation (CPM), which is a kind of endogenous pain modulatory mechanisms, is impaired in chronic pain patients, though healthy subjects shows CPM effects. Thus, CPM could be applied for pain control in chronic pain patients as tailor-made medicine.
To establish tailor-made medicine, quantitative evaluation of CPM is needed. For the quantitative evaluation of CPM, a quantitative pressure algometer and a quantitative heat pain stimulator are developed.
It is shown that the quantitative pressure algometer and the quantitative heat pain stimulator are sufficient for a quantitative evaluation of CPM. The study results show that the developed method could be applied for pain control in chronic pain patients as tailor-made medicine.

Free Research Field

歯科麻酔学分野、疼痛治療学分野