Metabolic Flexibility in non-obese patients with type 2 diabetes mellitus: meal ingestion and daily physical activity

2014 Fiscal Year Final Research Report

• Project/Area Number: 25870233
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science; Environmental physiology(including physical medicine and nutritional physiology)
• Research Institution: The University of Electro-Communications
• Principal Investigator: OHKAWARA Kazunori 電気通信大学, 情報理工学(系)研究科, 准教授 (30631270)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 2型糖尿病 / 基質酸化

Outline of Final Research Achievements

There are many non-obese patients with type 2 diabetes mellitus in Japanese population however a diet therapy targeting them is not established based on scientific evidence. The purpose of this study was to investigate capacity of utilizing glucose and fat as energy sources in non-obese patients with type 2 diabetes mellitus. As results, their capacity of glucose and fat utilization could be attenuated therefor they cannot use both of fat and glucose as energy source efficiency after meal ingestion. Furthermore, spending a long time by very light activities may negatively influence insulin secretion.

Free Research Field

エネルギー代謝