The effects of unbalanced diet in childhood on erectile function in adulthood

2015 Fiscal Year Final Research Report

• Project/Area Number: 25870611
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Urology; Medical pharmacy
• Research Institution: Nagoya City University
• Principal Investigator: Hotta Yuji 名古屋市立大学, 薬学研究科(研究院), 助教 (90637563)
• Research Collaborator: KIMURA Kazunori 名古屋市立大学, 大学院医学研究科, 教授 ; MAEDA Yasuhiro 名古屋市立大学, 大学院薬学研究科, 講師 ; KATAOKA Tomoya 名古屋市立大学, 大学院医学研究科, 助教
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 勃起機能 / 果糖 / 小児 / 終末糖化産物

Outline of Final Research Achievements

We investigated whether unbalanced diet in childhood affected erectile function in adulthood using young rats. First, we found that excessive fructose consumption in childhood induced erectile dysfunction in adulthood via the production of advanced glycation end products. Next, we examined whether the erectile dysfunction persisted after the stop of excessive fructose consumption and found that the erectile function recovered after the stop of excessive fructose consumption. Therefore, it is suggested that the excessive fructose consumption in childhood should be avoided to preserve erectile function in adulthood.

Free Research Field

男性性機能障害