Effects of thermal load on blood insulin sensitivity

2016 Fiscal Year Final Research Report

• Project/Area Number: 25870939
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Fundamental nursing; Clinical nursing
• Research Institution: Baika Women's University
• Principal Investigator: Nagai Masayo 梅花女子大学, 看護保健学部, 助教 (60623551)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 温熱刺激 / 骨格筋 / 生活習慣病予防

Outline of Final Research Achievements

The present study examined the effects of hot fomentation on metabolism by applying thermal sheets to thigh skeletal muscles. The subjects were twelve healthy people who were asked to apply thermal loads to the thigh skeletal muscles for ten weeks.Following the application, a significant increase was noted in serum adiponectin (p=0.033), but no significant change was noted in the fasting serum insulin, serum glucose and HOMA-IR. In women, a significant decrease was noted in the serum soluble form of urokinase type plasminogen activator receptor (p=0.046).Thermal load to the skeletal muscles caused a rise in the serum adiponectin, suggesting that this manipulation reduced body fat, elevated blood temperature, and increased blood flow to stimulate adiponection secretion from the adipocytes.
Although this thermal stimulation also induced changes in the gene expression of factors promoting ASCVD, the protective effects of thermal stimulation against ASCVD were predominant in SkMC.

Free Research Field

基礎看護学