2015 Fiscal Year Final Research Report
The utility of adrenaline beta3 receptor agonist as a new drug for Parkinson's disease
Project/Area Number |
25870943
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Pharmacology in pharmacy
General pharmacology
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Research Institution | Setsunan University |
Principal Investigator |
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | パーキンソン病 / β3受容体作用薬 / 神経保護作用 |
Outline of Final Research Achievements |
I investigated that adrenaline β3 receptor agonist could be a new drug for Parkinson's disease using MPTP-induced mouse Parkison's disease model. β3 receptor agonist increased glutathione levels in mouse brain and inhibited MPTP-induced death of dorpaminergic neurons.
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Free Research Field |
神経薬理学
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