2014 Fiscal Year Final Research Report
Identification and analysis of chemicals that affect RNA silencing in plants.
Project/Area Number |
25871119
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Plant molecular biology/Plant physiology
Chemical biology
|
Research Institution | The Institute of Physical and Chemical Research |
Principal Investigator |
KURIHARA Yukio 独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (60455342)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Keywords | RNAサイレンシング / ケミカル / 阻害 / 植物 |
Outline of Final Research Achievements |
Aim of this research is to identify novel chemicals that inhibit RNA silencing in plants. I performed chemical screening and then some experiments using molecular biological approaches. I found one special chemical as a final candidate of interest. Arabidopsis plants treated with this chemical showed increased accumulation of not only proteins and mRNAs of a target gene but also siRNAs which indicate occurrence of RNA silencing.
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Free Research Field |
植物分子生物学
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