2015 Fiscal Year Final Research Report
Function of IELs in the development of IBD.
Project/Area Number |
25871164
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Gastroenterology
Digestive surgery
|
Research Institution | National Center for Global Health and Medicine |
Principal Investigator |
ODA Hiroyo 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員 (10450595)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Keywords | 非典型T細胞 / 胸腺特異的遺伝子 / 自己免疫 |
Outline of Final Research Achievements |
Dysregulation of immune response plays important roles in the pathogenesis of IBD. To understand the role of T cells in IBD, we focused on the function of T cell specific genes (ISC1~13) in the development and function of T cells. We newly identified 4 candidate proteins that can associate with ISC4 in T cells.
|
Free Research Field |
免疫学
|