2014 Fiscal Year Final Research Report
Risk factors for type 2 diabetes among individuals with impaired insulin secretion
| Project/Area Number |
25882019
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Applied health science
|
|---|
| Research Institution | Shiga University of Medical Science |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2013-08-30 – 2015-03-31
|
| Keywords | インスリン分泌不全 / インスリン抵抗性 / 糖尿病 / 危険因子 |
|---|
| Outline of Final Research Achievements |
This study included individuals without diabetes at baseline who underwent comprehensive medical check-ups at Saku Central Hospital. Moderate and large increases in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes regardless of baseline HOMA-IR values among individuals with impaired insulin secretion in this Japanese population. Moreover, metabolic factors had a strong impact on the development of type 2 diabetes among individuals with impaired insulin secretion, compared with individuals with insulin resistance.
|
| Free Research Field |
保健学
|
