The effects of exercise training on the level of adropin

2015 Fiscal Year Final Research Report

• Project/Area Number: 25882039
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Doshisha University
• Principal Investigator: Hieda Mutsuko 同志社大学, スポーツ健康科学部, 助教 (70707455)
• Project Period (FY): 2013-08-30 – 2016-03-31
• Keywords: 運動トレーニング

Outline of Final Research Achievements

Adropin is a new peptide hormone that regulates lipid and glucose homeostasis. Also, adropin plays important roles in regulating endothelial functions. This study aims to evaluate whether exercise affects the level of adropin in obese rats. The Zucker fatty rats were randomly assigned to one of two groups: an exercise-trained group (ZFE) and a sedentary one (ZFC). ZFE was trained on a treadmill for 5days/week for 6 weeks. In addition, the Zucker lean rats were subjected to identical sedentary (ZLC). Rats were sacrificed 24h after the last training period, and their blood and some of their organs were collected. Body weight was lower in the ZFE compared to the ZFC. Plasma adropin was the highest in the ZFE among three groups. The findings of this study suggest that exercise training would increase adropin concentration in obese rats.

Free Research Field

運動生理学