Membrenome Drug Discovery -Control of recognition, fusion and regulation of drug carrier-

2014 Fiscal Year Final Research Report

• Project/Area Number: 25889065
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Biofunction/Bioprocess
• Research Institution: Nara National College of Technology
• Principal Investigator: HAYASHI Keita 奈良工業高等専門学校, その他部局等, 助教 (10710783)
• Project Period (FY): 2013-08-30 – 2015-03-31
• Keywords: Drug Delivery System / Self-assembly / Vesicle

Outline of Final Research Achievements

It has been investigated to active targeting for cancer cells by using biomolecules, such as anti-body and lectin. Drug encapsulating vesicles, such as liposomes and niosomes, were immobilized by these biomolecules in order to deliver efficiently and specifically drug for cancer cells. In recent years, Development of cancer cell targeting biomolecules has been investigated frequently. On the other hand, it has been hardly investigated about an optimal vesicle in spite of development of various kinds of vesicles. In this study, not only cancer cell targeting biomolecules, but also an optimal vesicle has been investigated. This result supported to improve drug delivery efficiency.

Free Research Field

生物機能・バイオプロセス