Clinical trial of combination therapy with methimazole and a cholesterol absorption inhibitor as for the initial treatment of childhood-onset Graves disease

2014 Fiscal Year Final Research Report

• Project/Area Number: 25893078
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Pediatrics
• Research Institution: Niigata University
• Principal Investigator: NAGASAKI Keisuke 新潟大学, 医歯学総合病院, 講師 (70419315)
• Co-Investigator(Renkei-kenkyūsha): HASEGAWA Yukihiro 東京都立小児総合医療センター, 臨床研究部, 部長 (70172898) ; SAWADA Hirotake 宮崎大学, 医学部, 講師 (40332895) ; TAKUBO Noriyuki 一般財団法人脳神経疾患研究所, 医学系研究科, 科長 (20306583) ; TAKAKUWA Satoshi 大阪大学, 医学系研究科, 特任助教 (00331643)
• Project Period (FY): 2013-08-30 – 2015-03-31
• Keywords: バセドウ病 / 多施設共同研究 / 初期治療

Outline of Final Research Achievements

We set up to undergo multicenter clinical trial. At first, we made a research project with members, and the project was approval by our institutional review board. A questionnaire was made in councilors of the The Japanese Society for Pediatric Endocrinology and was able to obtain the participation of 26 institutions. After approval of the project, we prepared to start the clinical trial, while having preparations for randomization systems (University Hospital Clinical Trial Alliance). This clinical trial have been registered in 26th Jun 2014 as UMIN000014383 and now we are handling this registration.

Free Research Field

医歯薬学